The alternative pathway of the complement system is implicated in the etiology of age-related macular degeneration (AMD). Complement depletion with pegcetacoplan and avacincaptad pegol are FDA-approved treatments for geographic atrophy in AMD that. while effective. have clinically observed risks of choroidal neovascular (CNV) conversion. https://www.sjcaindia.com/product-category/12-inch-ep/