When inferring phylogenetic relationships. not all sites in a sequence alignment are equally informative. One recently proposed approach that takes advantage of this inequality relies on sites that contain amino acids whose replacement requires multiple substitutions. Identifying these so-called RGC_CAM substitutions (after Rare Genomic Changes as Conserved Amino acids-Multiple substi... https://www.markymarkscott.com/product-category/soft-sculpting-spray-gel/